1942 Japan, the village of Hanyuda is gripped by an unspeakable evil. Following an earthquake, a loud siren sounds and the surrounding sea has turned blood, engulfing much of the town. The villagers seem to be transforming into lumbering zombies at an alarming rate. Siren's story unfolds through the eyes of its ten lead characters, as they struggle to survive the chaos of a village gone seriously awry.