| Shining in the Darkness
| 010086013108 | | 1991-0-0
|
| Sesame Street Countdown
| 087855000041 | | 1991-0-0
|
| Strider
| | | 1991-0-0
|
| Sonic the Hedgehog
| | | 1991-0-0
|
| The Simpsons: Bart vs. the World
| 021481105053 | NES-Y9-USA | 1991-0-0
|
| Slaughter Sport
| 720326805379 | | 1991-0-0
|
| Star Trek: 25th Anniversary
| 083717120179 | | 1991-0-0
|
| Star Wars
| 009119910125 | | 1991-0-0
|
| Super Pang
| | | 1991-0-0
|
| Super Spike V'Ball / Nintendo World Cup
| | NES-QJ-USA | 1991-0-0
|
| Sherlock Holmes: Consulting Detective
| 092218001108 | TXCD1011 | 1991-0-0
|
| Super Castlevania IV
| 083717150015 | | 1991-1-0
|
| Star Control
| 015605031021 | | 1991-2-17
|
| Sangokushi: Eiketsu Tenka ni Nozomu
| 4988658901022 | NXCD0002 | 1991-3-29
|
| Sonic the Hedgehog
| 4974365624088 | | 1991-4-0
|
| Super Volleyball
| 010086012125 | 1212 | 1991-4-15
|
| Sim City
| 4902370501292 | SHVC-SC | 1991-4-26
|
| Starflight
| 014633070149 | | 1991-5-0
|
| Shinobi
| 010086024029 | | 1991-6-0
|
| Street Fighter II
| 013388130054 | | 1991-6-1
|
| Space Adventure Cobra II: Densetsu No Otoko
| 4988607250218 | HCD1014 | 1991-6-7
|
| Sengoku Kantou Sangokushi
| 4959179911012 | IGCD1002 | 1991-6-28
|
| Splash Lake
| 4988041700294 | NAPR-1020 | 1991-6-28
|
| The Super Spy
| | | 1991-7-1
|
| Sengoku
| | | 1991-7-1
|
| Seirei Senshi Spriggan
| 4988658911038 | NXCD1004 | 1991-7-12
|
| Super R-Type
| 4962891800014 | SHVC-SR | 1991-7-13
|
| Sherlock Holmes no Tantei Kouza
| 4988002221547 | JCCD1004 | 1991-7-26
|
| Sonic The Hedgehog
| 4974365540494 | G-4049 | 1991-7-26
|
| Seiryuu Densetsu Monbit
| 4988607250188 | HCD1018 | 1991-8-30
|
| Sim City
| 045496830038 | | 1991-9-0
|
| Super Mario World
| 045496830014 | | 1991-9-9
|
| Super Soccer Champ
| 020588010468 | | 1991-10-0
|
| Super Baseball 2020
| 724678245845 | | 1991-10-25
|
| Secret Weapons of the Luftwaffe
| 023272988692 | | 1991-11-0
|
| Super Baseball Simulator 1.000
| 047743950162 | | 1991-11-0
|
| SmartBall
| 090451304024 | | 1991-11-0
|
| Super Bases Loaded
| 032264700013 | | 1991-11-0
|
| Super Tennis
| 045496830083 | | 1991-11-0
|
| Sagaia
| 020588010345 | 11016 | 1991-11-0
|
| Super Schwarzschild
| 4959067910028 | KSCD1002 | 1991-12-6
|
| Super Wagyan Land
| 4907892070011 | SHVC-SW | 1991-12-13
|
| Super CD-ROM² Taiken Soft Shuu
| 4988607250287 | HCD1027 | 1991-12-13
|
| Super Fire Pro Wrestling
| 4959143600010 | SHVC-FP | 1991-12-20
|
| Sim Earth: The Living Planet
| 4965857005027 | SHVC-SE | 1991-12-29
|
| Sonic the Hedgehog
| 100860100916 | | 1991-12-31
|
| Spider-Man: Return of the Sinister Six
| 023582051888 | | 1992-0-0
|
| Super Smash TV
| 021481601029 | | 1992-0-0
|
| Super High Impact
| 734549001067 | | 1992-0-0
|
| Stunt Island
| | | 1992-0-0
|